Maybe it’s not about humans and never has been. Maybe by the time the gods realized how much of an issue humans were, we were already too widespread for them to destroy us without either running out of mana or ruining earth for everything.
Maybe the cancer is a god’s plan, but it’s not working well enough.
Any of those topics that people who care more about society being polite than just tell you to avoid are ones that should be not just discussed but agreed on before making a relationship legally binding. Religion, money, politics. They are each too serious for “agree to disagree” to last long.