A spice used in Indian cuisine. It’s intensely yellow due to curcumin, a compound that has miraculous property of causing false positives in about any cell assay (ie it seems like it does something, but really it decomposes/is fluorescent/damages cell wall/clumps up/pulls metal ions where they shouldn’t be/forms hydrogen peroxide where it shouldn’t be, all of which can look like some kind of activity when looking at cells, but it is not so)
Also it’s completely insoluble in water and shredded by liver in minutes, so it’s physically impossible for it to be active in vivo (can’t do shit if it’s not there). It’s great for churning out bad science tho
It is used in ayurveda, and some proponents of ayurveda want to prove that it cures literally everything, and its behaviour in cell assays makes it seem so at least as long as you don’t look too closely
I’d say it’s worse than placebo, because it’s known by now that nothing of that shit has any chance to work yet there are still clinical trials with it. This takes away resources from things that have a better shot at working which imo makes it pretty unethical
A spice used in Indian cuisine. It’s intensely yellow due to curcumin, a compound that has miraculous property of causing false positives in about any cell assay (ie it seems like it does something, but really it decomposes/is fluorescent/damages cell wall/clumps up/pulls metal ions where they shouldn’t be/forms hydrogen peroxide where it shouldn’t be, all of which can look like some kind of activity when looking at cells, but it is not so)
Also it’s completely insoluble in water and shredded by liver in minutes, so it’s physically impossible for it to be active in vivo (can’t do shit if it’s not there). It’s great for churning out bad science tho
It is used in ayurveda, and some proponents of ayurveda want to prove that it cures literally everything, and its behaviour in cell assays makes it seem so at least as long as you don’t look too closely
I’d say it’s worse than placebo, because it’s known by now that nothing of that shit has any chance to work yet there are still clinical trials with it. This takes away resources from things that have a better shot at working which imo makes it pretty unethical