Just a thought I had, like what can a ten year old do(besides mass murder & accidents) that messes up their life so badly that it is unrecoverable?
It has to be something that is self inflicted and not something that is the cause of others around them.
Be born a woman in Afghanistan… come out the womb to “And that’s when she knew she had fucked up.”
I’m not certain if this is in the spirit of your question but even a murderer in the US has privileges denied to a lot of other people.